Repurposing Plant Virus Nanoparticles

Multifunctional Therapeutics using Engineered Plant Virus Nanoparticles

Repurposing of prochlorperazine for use against dengue virus infection.

The increasing prevalence of dengue virus (DENV) infection presents serious disease and economic burdens in countries where dengue epidemics are occurring. Despite the clinical importance, no DENV vaccine or anti-DENV drug is available. In this study, we found that prochlorperazine (PCZ), a dopamine D2 receptor (D2R) antagonist approved to treat nausea, vomiting, and headache in humans has pote...

Plant Extracts Derived Silver Nanoparticles

Nanotechnology is a most promising field for generating new applications in medicine. The present investigation is highly warranted to through more light upon the Ag nanoparticles from medicinal plants will helpful to investigate the active principle action for biochemical and molecular fields. In this study, nanoparticles of 80 ± 90 nm were synthesized by using medicinal plants such as Mukia m...

Virus templated metallic nanoparticles.

Plant viruses are considered as nanobuilding blocks that can be used as synthons or templates for novel materials. Cowpea mosaic virus (CPMV) particles have been shown to template the fabrication of metallic nanoparticles by an electroless deposition metallization process. Palladium ions were electrostatically bound to the virus capsid and, when reduced, acted as nucleation sites for the subseq...

Plant Virus Ecology

Viruses have generally been studied either as disease-causing infectious agents that have a negative impact on the host (most eukaryote-infecting viruses), or as tools for molecular biology (especially bacteria-infecting viruses, or phage). Virus ecology looks at the more complex issues of virus-host-environment interactions. For plant viruses this includes studies of plant virus biodiversity, ...